Insights   |   October 15, 2024

Uncovering Opportunities in Small/Mid Cap Equity

Institutional investors seeking high-growth potential with a calculated risk profile should consider the dynamic landscape of small and mid cap (SMID) companies in healthcare and technology. These sectors boast a wealth of innovation, often driven by nimble and adaptable players poised for significant disruption. 

The Fiera Apex team sees several secular themes around driving efficiency and finding novel solutions in the Healthcare and Technology sectors which make small and mid-cap companies attractive investment opportunities.

Healthcare

Driven by prolific innovation, along with demographic tailwinds, resilient demand, and strong fundamentals, we believe SMID cap healthcare holds some of the greatest potential for long-term growth.

Within the SMID biotech subsector, significant opportunities can be found in companies that focus on addressing unmet medical needs with de-risked clinical assets and broad market upside. Prescription drug spend in the United States is over $400 billion annually and growing. However, current FDA-approved therapies address only a fraction of defined illnesses, reflecting vast, untapped TAMs waiting for solutions. Concentrated on R&D and supported by ongoing advances in life science technologies, SMID biotech is poised to deliver numerous near-term breakthroughs across the spectrum of human health, from the leading causes breakthroughs across the spectrum of of death, such as heart disease and cancer, to rare orphan indications, like Huntington’s and muscular dystrophy. 

More broadly, we also look for companies that focus on reining in the costs of healthcare. Annual US health expenditure is currently about $4.5 trillion or 17% of GDP, about one-quarter of which is considered waste. This includes problems such as improper diagnoses and treatment, administrative complexity, and other failures of care coordination. The companies we favor under this theme are those that work to improve the quality and sustainability of the healthcare system, including improved disease detection, home health services, and healthcare IT solutions.

[…]

Related Insights

Abstract background with dark blue and arrows
Insights
April 15, 2026

Q2 2026 Investment Outlook & Portfolio Strategy

Read our latest quarterly Investment Outlook and Portfolio Strategy document, providing a financial market recap for Q1 and our outlook for the next 12-18 months.
Fiera Apex: Growth In Focus, Sunil Reddy
Equities
April 14, 2026

Fiera Apex: Growth In Focus

Sunil Reddy, Lead Portfolio Manager and Head of Fiera Apex Growth Equities reviews key themes that shaped growth equity markets in Q1 2026 and what the team sees on the horizon.
Sunil Reddy
Head of Fiera Apex, Lead Portfolio Manager